Laboratory of laser molecular spectroscopy

Research topics:

The triangle: carotenoids-retinoids-cytochromes plays a key role in development and progress of cancer
The application of Raman imaging and spectroscopy in lipidomic, proteomic, and epigenetic studies of normal and cancerous tissues and cells in the human brain, breast gland, lungs, and gastrointestinal tract, under both normal and oxidative stress conditions.
Studying the nanomechanical properties of human tissues and cells using AFM (Atomic Force Microscopy) and AFM-nano-IR techniques.
The application of fluorescence spectroscopy in studying the structure and metabolic pathways of human cells, and spectroscopic analysis of cell viability.
Femtosecond dynamics of molecular photoswitches from the diarylethene group.

Treść (rozbudowana)

News

Our PhD student, MSc Eng. Karolina Jarczewska, was awarded at the European Conference on the Spectroscopy of Biological Molecules 2024 (ECSBM2024), Lodz, 1-5 September 2024. Karolina received the 1st prize for her poster titled "Should I eat algae? The impact of fucoxanthin on astrocytoma cells" and the 2nd prize for her oral presentation titled "The impact of xanthophylls on brain and breast cancer development."

Stanford University has published the names of the top 2% of scientists in the world whose publications are most frequently cited by other authors. Among them was prof.dr hab. Halina Abramczyk from the Lodz University of Technology: link

On September 22, 2024, Prof. Halina Abramczyk delivered a presentation titled "A new modality for fertility and cancer tracking – Raman imaging, fluorescence and AFM studies combined with AI analysis" at the XVII INTERNATIONAL CONFERENCE ON MOLECULAR SPECTROSCOPY, held from September 22 to 25, 2024, in Wojanów, Poland.https://icms.intibs.pl/

Hemoglobin and cytochrome c. reinterpreting the origins of oxygenation and oxidation in erythrocytes and in vivo cancer lung cells,
H. Abramczyk, J. M. Surmacki, M. Kopeć, K. Jarczewska, B. Romanowska-Pietrasiak, 13 (2023), DOI: 10.1038/s41598-023-41858-z

Raman Spectroscopy and Imaging Studies of Human Digestive Tract Cells and Tissues—Impact of Vitamin C and E Supplementation
K. Beton-Mysur, B. Brozek-Pluska, Molecules, 28 (2023), DOI: 10.3390/molecules28010137

The Composite Material of (PEDOT-Polystyrene Sulfonate)/Chitosan-AuNPS-Glutaraldehyde/as the Base to a Sensor with Laccase for the Determination of Polyphenols
Paweł Krzyczmonik, Marta Klisowska, Andrzej Leniart, Katarzyna Ranoszek-Soliwoda, Jakub Surmacki, Karolina Beton-Mysur, Beata Brożek-Płuska, Polyphenols, Materials (Basel), 16 (2023) DOI: 10.3390/ma16145113.

Confocal Raman imaging reveals the impact of retinoids on human breast cancer via monitoring the redox status of cytochrome c
J.M. Surmacki, H. Abramczyk, Sci. Rep. 13 (2023) DOI: 10.1038/s41598-023-42301-z

Control of Mitochondrial Electron Transport Chain Flux and Apoptosis by Retinoic Acid: Raman Imaging In Vitro Human Bronchial and Lung Cancerous Cells
H. Abramczyk, J.M. Surmacki, Cancers, 15 (2023) Cancers 2023, DOI:10.3390/cancers15184535

Evaluation of Label-Free Confocal Raman Microspectroscopy for Monitoring Oxidative Stress In Vitro in Live Human Cancer Cells
J. M. Surmacki, I. Quiros-Gonzalez, S. E. Bohndiek, Antioxidants 11 (2022) 573, DOI: 10.3390/antiox11030573

Decoding the role of cytochrome c in metabolism of human spermatozoa by Raman imaging
H. Abramczyk, B. Sobkiewicz, R. Walczak-Jędrzejowska, K. Marchlewska, J. Surmacki, Front. Cell Dev. Biol., 10 (2022), DOI: 10.3389/fcell.2022.983993

Wide-range IR spectra of diarylethene derivatives and their simulation using the density functional theory
A. Jarota, D. Drwal, J. Pięta, E. Pastorczak, Scientific Reports, 12 (2022) 16834, DOI: 10.1038/s41598-022-20264-x

Hyperglycemia and Cancer in human lung carcinoma by means of Raman spectroscopy and imaging
M. Kopeć, K. Beton, K. Jarczewska, H. Abramczyk, Scientific Reports, 12 (2022) 18561, DOI: 10.1038/s41598-022-21483-y

Team

prof. dr hab. Halina Abramczyk
dr hab. inż. Beata Brożek-Płuska, prof. uczelni (head of the laboratory)
dr hab. inż. Jakub Surmacki
dr inż. Arkadiusz Jarota
dr inż. Monika Kopeć
mgr inż. Karolina Beton-Mysur
mgr inż. Karolina Jarczewska

Former members:

dr Rafał Kania
dr Marek Kołodziejski
dr Gabriela Waliszewska
dr Katarzyna Paradowska-Moszkowska
dr Iwona Szymczyk
dr Piotr Ciąćka
dr Gabriela Wiosna
mgr Agnieszka Lebioda
mgr Marta Jackowicz
mgr Marceli Rzetelski
mgr Marcel Sobkiewicz
mgr Krzysztof Kurczewski
mgr Małgorzata Kurczewska
mgr Izabela Placek
mgr Agata Bondarczuk
mgr Sylwia Kędzia
mgr Joanna Gudej
mgr Magdalena Janczak
mgr Sylwia Ferenc
mgr Agnieszka Wróblewska
mgr Magdalena Olejniczak
mgr Michalina Stokowska
mgr Olga Olejniczak
mgr Marek Barut
mgr Marta Smolnik
mgr Justyna Jatczak
mgr Marta Krześniak
mgr Monika Jędrzejczyk
mgr Katarzyna Biernacka
mgr Piotr Wysocki
inż. Paulina Piotrowicz
inż. Iga Dominiak
inż. Sandra Bełc
inż. Justyna Sala
inż. Julia Pędziwiatr

Collaboration

Department of Physics, University of Cambridge, Cambridge, UK
MAX BORN INSTITUTE for Nonlinear Optics and Short Pulse Spectroscopy, Berlin, Germany
Uniwersytet Medyczny w Łodzi, Katedra Onkologii, Zakład Patologii, Łódź, Polska
Uniwersytet Medyczny w Łodzi, Klinika Andrologii i Endokrynologii Rozrodu, Łódź, Polska
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi, Łódź, Polska
Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej – Centralny Szpital Weteranów, Klinika Chirurgii Ogólnej i Kolorektalnej, Łódż, Polska
Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej w Łodzi – Centralny Szpital Weteranów, Klinika Neurochirurgii, Chirurgii Kręgosłupa i Nerwów Obwodowych, Łódź, Polska
Instytut Centrum Zdrowia Matki Polki, Klinika Neurochirurgii i Neurotraumatologii, Łódź, Polska
Klinika Leczenia Niepłodności Salve Medica, Łódź, Polska